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CUSTOM HYBRIDOMA/MONOCLONAL ANTIBODY SERVICES
Signën Clinical Discoveries offers prompt, efficient custom services to develop
hybridomas and monoclonal antibodies at competitive prices. Our antibody screenings
are automated, which improves the quality and standardizes the production process. We
have more than 1,200 proteins available for use with ELISA, WB, antibody production,
assay development, and protein array. We guarantee the clones and resulting monoclonal
antibodies are your exclusive property and are held in strict confidence by our personnel.
Protein Expression and Monoclonal Antibody Production 
  Turn around time:  Clone Ownership: 
Customer Responsibility:  Customer provides the conjugated peptide immunogen for immunization and screening (required). Customer provides mammalian cell lysate for screening (optional). 
Signėn and/or partner Service:  Signėn performs immunization of 2 mice, fusion, screening and initial characterization (ELISA). The customer obtains up to three distinct monoclones and their supernatants from three polyclonal parent wells. More monoclones may be obtained upon request. 
Criteria of success:  The generated Monoclonal antibody will recognize peptide immunogen in an ELISA assay. 
Protein Expression and Monoclonal Antibody Production 
  Turn around time:  Clone Ownership: 
6 months  Customer 
Customer Responsibility:  Customer provides the soluble protein immunogen for immunization and screening (At least 1mg total for 2 mice immunization or 500mg for 1 mouse immunization). Customer provides mammalian cell lysate for screening (optional). 
Signėn and/or partner Service:  Signėn performs immunization of 2 mice, fusion, screening and initial characterization (Dot Blot/ELISA and WB). The customer obtains up to three distinct monoclones and their supernatants from three polyclonal parent wells. More monoclones may be obtained upon request. 
Criteria of success:  The generated Monoclonal antibody will recognize protein immunogen in an ELISA assay.