Signën Clinical Discoveries offers prompt, efficient custom services to develop hybridomas and monoclonal antibodies at competitive prices. Our antibody screenings are automated, which improves the quality and standardizes the production process. We have more than 1,200 proteins available for use with ELISA, WB, antibody production, assay development, and protein array. We guarantee the clones and resulting monoclonal antibodies are your exclusive property and are held in strict confidence by our personnel.
Protein Expression and Monoclonal
Antibody Production
Turn around
time:
Clone Ownership:
Customer
Responsibility:
Customer provides the conjugated
peptide immunogen for immunization and screening (required). Customer
provides mammalian cell lysate for screening (optional).
Signėn and/or partner Service:
Signėn performs immunization of 2
mice, fusion, screening and initial characterization (ELISA). The customer
obtains up to three distinct monoclones and their supernatants from three
polyclonal parent wells. More monoclones may be obtained upon request.
Criteria
of success:
The generated Monoclonal antibody
will recognize peptide immunogen in an ELISA assay.
Protein Expression and Monoclonal
Antibody Production
Turn
around time:
Clone
Ownership:
6
months
Customer
Customer Responsibility:
Customer
provides the soluble protein
immunogen for immunization and screening (At least 1mg total for 2 mice
immunization or 500mg for 1 mouse immunization). Customer provides mammalian
cell lysate for screening (optional).
Signėn and/or partner
Service:
Signėn performs immunization of 2
mice, fusion, screening and initial characterization (Dot Blot/ELISA and WB).
The customer obtains up to three distinct monoclones and their supernatants
from three polyclonal parent wells. More monoclones may be obtained upon
request.
Criteria of success:
The generated Monoclonal antibody
will recognize protein immunogen in an ELISA assay.